School of Medicine

Wayne State University School of Medicine
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About the Department

Biochemistry and Molecular Biology have become central to the biological revolution that is transforming the life of all humans. Our goal is to prepare students for active participation in this exciting area of human endeavor, by investigating the molecular mechanisms underlying biological processes, with emphasis by focusing on the relationship between macromolecular structure and function. Our research programs range from investigations of the detailed interactions of biological molecules and to broad studies of evolutionary processes. The department has undergone a major expansion in the area of in structural biology, with new faculty who have nationally ranked programs in x-ray crystallography and nuclear magnetic resonance. Read more.

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Calendar of Events

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Congenital Heart Disease for the Adult Cardiologist
August 29 2016 at 12:00 PM
DMC Heart Hospital
Featuring Dr. Ramanjit Kaur. Presented by the WSU Department of Internal Medicine.
IBio Seminar with Wanqing Liu, Ph.D., Purdue University - Nonalcoholic Fatty Liver Disease (NAFLD): Genetics, Genomics and Precision Medicine
August 29 2016 at 1:15 PM
Integrative Biosciences Center
The Wayne State University community is invited to attend an IBio Seminar with guest speaker, Wanqing Liu, assistant professor of Medicinal Chemistry and Molecular Pharmacology at Purdue University's College of Pharmacy, on Monday, August 29, 2016 at 1:15 p.m. in the seminar room of IBio. Dr. Liu will present "Nonalcoholic Fatty Liver Disease (NAFLD): Genetics, Genomics and Precision Medicine." NAFLD is the most common chronic liver disease with only very limited treatment options available. Genetic and genomic studies on NAFLD in the past 10 years have identified a few important genetic loci strongly conferring risks to the development and progression of the disease. Using an integrated omics-based approach, Dr. Liu and his research team have recently revealed that Fatty Acid Desaturase 1 (FADS1) is a key gene involved in hepatic fat accumulation and NAFLD by modulating the composition of polyunsaturated fatty acids (PUFAs) in human livers. Via further mechanistic analyses, they have delineated the molecular pathways underlying FADS1 and hypothesized a genotype-based treatment strategy for NAFLD using omega-3 PUFA. In addition, their genetic and genomic studies also paved the basis for precision treatment of NAFLD by targeting other key genes and microRNAs for NAFLD. Dr. Liu received his B.S. in Biological Sciences Education from Shandong Normal University, China in 1996 and his Ph.D. in Neurobiology in 2001 from Shanghai Institute of Physiology, Chinese Academy of Sciences, Shanghai, China. From 2002-2011, he was a Research Associate, followed by a Research Assistant Professor at the University of Chicago where his research was focused on pharmacogenomics, cancer genomics and personalized medicine. He is currently an assistant professor of Medicinal Chemistry and Molecular Pharmacology in the College of Pharmacy at Purdue University. His research interests include both genomics of human diseases and personalized medicine. His specific projects are currently concentrated on understanding the pharmacogenomics of hepatic lipid metabolism in humans and genetic susceptibility to liver diseases. In addition, his group is also working to identify the genetic mechanism underlying the susceptibility to human lung cancer. Dr. Liu and his lab have published over 65 peer-review articles with many of them published on top-tier journals. His research has been broadly funded by the National Institutes of Health, American Cancer Society, as well as other foundation.  
Laboratory Safety Training
August 29 2016 at 1:30 PM
This training addresses issues related to chemical safety, chemical waste disposal, and emergency procedures in the laboratory. It is required once for all employees who work in a lab with hazardous chemicals. This class combines the former OSHA Laboratory Standard and the Hazardous Waste & Emergency Procedures classes. Topics covered: Contents of the OSHA Lab Standard (29 CFR 1910.1450) WSU Chemical Hygiene Plan Physical and health hazards of chemicals Safety equipment in the laboratory Safe handling and storage of chemicals Safety Data Sheets, Hazard Classification & Labeling Personal protective equipment Explanation of EPA, MDEQ, and DOT regulations Explanation of the WSU Emergency Contingency Plan Laboratory employee's responsibilities as a hazardous waste generator Definitions of hazardous waste Procedures for collection, labeling, storage and removal of waste Responding to injuries, spills, fires, and other emergencies in the laboratory Click here to view the Laboatory Safety Powerpoint Presentation (note: viewing these slides does not count as training!)  
Pulmonary Sleep Medicine Core Lectures and Case Conference
August 30 2016 at 11:00 AM
Harper University Hospital
Presented by the WSU Department of Internal Medicine.
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