EducationPh.D., New York University, NY, NY, 1987...

Education:Ph.D. Microbiology, Ohio State University, 1981Activities:Director, Master’s Program Biochemistry and Molecular Biology Co-founder, Antimicrobial Resistance Research Group, WSU Research:Microbiomics, fungal molecular diagnostics, antifungal resistance  ...

Education Ph.D. University of Wisconsin, Madison, WI, 1980...

EducationPh.D., University of Washington, 1959...

My laboratory uses X-ray crystallography to elucidate the structure-function relationships of proteins. Presently, our projects cluster into two areas:Arsenate reduction The R773 plasmid of Escherichia coli encodes a system for...

We are studying the structure and function of large complex multidomain proteins. Much of our work focuses on the CAD, a 1.5 megadalton complex that catalyzes the initial steps in...

 

My lab is interested in two different areas, although both have something to do with the human erythrocyte. We work on the effect of oxidative damage on erythrocyte function, using...

Our laboratory performs structure-function studies of viral drug targets using structural, biochemical and computational methods. We use X-ray crystallography and molecular modeling to explore HIV drug resistance, perform structure-based drug...

Our research interest has been centered in the field of mitochondrial bioenergetics and mitochondrial pathophysiology. Mitochondrial diseases occupy at present a highly active area of investigation in both molecular and...

Our research is focused on understanding the structural and functional aspects of membrane proteins and their interactions with other proteins in compartmentalized microdomains of cells and their roles in health...

 

 

Transition metals such as zinc, iron and copper are essential for life and act as cofactors in proteins and as signaling systems. However, they can be toxic in excess. Other...

Yeast molecular genetics: We have elucidated the maltose fermentation system in S. cerevisiae by cloning the genes of the polymeric MAL system, describing their organization, purifying the activator protein, identifying...

The biological regulation of iron is essential for the viability of numerous organisms.  In humans, iron is essential for a variety of cellular processes including blood formation/oxygen transport, immune response...

Education:1948-52 American University of Beirut, B.A. Chemistry1952-54 American University of Beirut, M. A. Physical Chemistry1954-59 Illinois Institute of Technology, Ph.D. Physical Chemistry1959-1962 Postdoctoral Fellow, Chemistry Department, University of Alberta, Edmonton,...

Research in our laboratory focuses on two major human diseases: heart disease and Alzheimer's disease. We are using structural biology, molecular biology, protein chemistry, biophysics and protein engineering techniques in...

My laboratory are interested in structure and function of disease-related proteins. One of our current focuses is a cardiac specific histone methyltransferase, which has been linked to end-stage heart failure...

Research in our laboratory follows two main themes. One is directed at understanding how regulatory networks control biological processes. Our approach is to identify and characterize networks of interacting genes...

Overproduction of reactive oxygen species (ROS) have been implicated as important pathogenic mediators in many clinical disorders such as hyperoxic lung injury and ischemia/reperfusion- and adriamycin (ADR)-induced cardiac damage. The...

Our team studies mitochondrial function using genetic and biochemical approaches. We focus on two key components of the mitochondrial oxidative phosphorylation machinery, cytochrome c oxidase (COX) and the small electron...

Our primary research interests are cilium and flagellum that are evolutionarily related sensory organelles.  Projecting like an antenna on the cell surface, cilia are found on most of our bodily...