School of Medicine

Wayne State University School of Medicine

Faculty Profiles

Primary Faculty

Sharon Ackerman
Title
Associate Professor
Phone
313-577-5016
Profile
EducationPh.D., New York University, NY, NY, 1987...
Robert Akins
Title
Associate Professor
Phone
313-577-0419
Profile
Education:Ph.D. Microbiology, Ohio State University, 1981Activities:Director, Masterís Program Biochemistry and Molecular Biology Co-founder, Antimicrobial Resistance Research Group, WSU Research:Microbiomics, fungal molecular diagnostics, antifungal resistance  ...
William S. Brusilow
Title
Professor
Phone
313-577-6659
Profile
Education Ph.D. University of Wisconsin, Madison, WI, 1980...
Brian F.P. Edwards
Title
Professor
Phone
313-577-1506
Profile
My laboratory uses X-ray crystallography to elucidate the structure-function relationships of proteins. Presently, our projects cluster into two areas:Arsenate reduction The R773 plasmid of Escherichia coli encodes a system for...
Biochemistry/Microbiology: David Evans, Ph.D.
Title
Professor
Phone
313-577-1016
Profile
We are studying the structure and function of large complex multidomain proteins. Much of our work focuses on the CAD, a 1.5 megadalton complex that catalyzes the initial steps in...
Domenico L. Gatti, M.D., Ph.D
Title
Associate Professor
Phone
313-993-4238
Profile
My laboratory is involved in the development of new computational tools to study enzyme mechanisms and metabolic pathways, and to identify coevolving elements inside protein structures.View Laboratory Website. ...
Ladislau C. Kovari, Ph.D.
Title
Associate Professor of Biochemistry and Molecular Biology
Phone
313-993-1335
Profile
Our laboratory performs structure-function studies of viral drug targets using structural, biochemical and computational methods. We use X-ray crystallography and molecular modeling to explore HIV drug resistance, perform structure-based drug...
Chunying Li, Ph.D
Title
Assistant Professor
Phone
(313) 577-4182
Profile
Our research is focused on understanding the structural and functional aspects of membrane proteins and their interactions with other proteins in compartmentalized microdomains of cells and their roles in health...
James Lightbody
Title
Associate Professor
Phone
313-577-1505
Profile
 
Bharati Mitra
Title
Interim Chair
Professor
Phone
313-577-0040
Profile
Transition metals such as zinc, iron and copper are essential for life and act as cofactors in proteins and as signaling systems. However, they can be toxic in excess. Other...
Richard Needleman
Title
Professor
Phone
313-577-1426
Profile
Yeast molecular genetics: We have elucidated the maltose fermentation system in S. cerevisiae by cloning the genes of the polymeric MAL system, describing their organization, purifying the activator protein, identifying...
Serge Nicholas Vinogradov
Title
Professor
Phone
313-577-1501
Profile
Education:1948-52 American University of Beirut, B.A. Chemistry1952-54 American University of Beirut, M. A. Physical Chemistry1954-59 Illinois Institute of Technology, Ph.D. Physical Chemistry1959-1962 Postdoctoral Fellow, Chemistry Department, University of Alberta, Edmonton,...
Jianjun Wang Ph.D.
Title
Professor
Phone
313-577-8836
Profile
Research in our laboratory focuses on two major human diseases: heart disease and Alzheimer's disease. We are using structural biology, molecular biology, protein chemistry, biophysics and protein engineering techniques in...
Zhe Yang
Title
Assistant Professor
Phone
313-577-1294
Profile
My laboratory is interested in structure and function of disease related proteins. Our current focuses include cardiac specific histone methyltransferases, DNA demethylases, and histone demethylases. These proteins are related to...

Emeritus Faculty

Robert M. Johnson
Title
Professor Emeritus
Phone
313-577-1816
Profile
My lab is interested in two different areas, although both have something to do with the human erythrocyte. We work on the effect of oxidative damage on erythrocyte function, using...
Chuan-Pu Lee
Title
Distinguished Professor Emerita
Phone
313-577-1158
Profile
Our research interest has been centered in the field of mitochondrial bioenergetics and mitochondrial pathophysiology. Mitochondrial diseases occupy at present a highly active area of investigation in both molecular and...

Associate Faculty

Russell L. Finley Jr.
Title
 
Phone
313-577-7845
Profile
Research in our laboratory follows two main themes. One is directed at understanding how regulatory networks control biological processes. Our approach is to identify and characterize networks of interacting genes...
Ye-Shih Ho
Title
Professor
Phone
313-963-7660
Profile
Overproduction of reactive oxygen species (ROS) have been implicated as important pathogenic mediators in many clinical disorders such as hyperoxic lung injury and ischemia/reperfusion- and adriamycin (ADR)-induced cardiac damage. The...
Maik Huttemann
Title
Associate Professor
Phone
(313) 577-9150
Profile
Our team studies mitochondrial function using genetic and biochemical approaches. We focus on two key components of the mitochondrial oxidative phosphorylation machinery, cytochrome c oxidase (COX) and the small electron...
Xiangyi Lu
Title
Associate Professor
Phone
313-963-7872 (Office)
313-577-0100 (Main office)
313-964-2269 (Lab)
Profile
Our primary research interests are cilium and flagellum that are evolutionarily related sensory organelles.  Projecting like an antenna on the cell surface, cilia are found on most of our bodily...

Secondary Faculty

Timothy Stemmler
Title
Professor
Phone
313- 577-5712
Profile
The biological regulation of iron is essential for the viability of numerous organisms.  In humans, iron is essential for a variety of cellular processes including blood formation/oxygen transport, immune response...